What is Lipolysis?

Lipolysis is a minimally invasive, non-surgical injection method for melting localized fat deposits. It involves the use of active substances that are injected directly into the excess fat tissue, thereby reducing it.

Lipolysis dates back to 1952 in France and was officially recognized in 1987, becoming part of medical procedures.


How Does Lipolysis Work?

What Lipolysis Involves:

Lipolysis uses lipolytics, which contain phosphatidylcholine (PPC) as the main substance. This enzyme breaks down the fat cell wall, resulting in the resorption and elimination of the fat cell's content.

Procedure and Number of Treatments:

After a medical examination and indication for lipolysis, lipolytic agents are injected directly into the localized fat deposits using fine needles. This causes the fat to dissolve in the desired region. The duration of the procedure depends on the treated area, usually lasting from 30 to 60 minutes. The number of treatments depends on the amount of fat tissue. For complete results, a series of 4-6 treatments with a one-month interval is recommended.

Mechanism of Action:

Lipolysis achieves the complete destruction of fat cells, breaking down the fat cell wall and connective partitions, reducing fat tissue in the treated region. The applied lipolytic agent melts the fat cells, releasing fatty acids, which are then hydrolyzed and made water-soluble. These fatty acids signal macrophages to rapidly migrate to the site and transport the fatty acids to the liver for further metabolism and elimination from the body.

Effects of Lipolysis

Lipolysis is a treatment that reduces the volume of the desired region without reducing body weight. It is equally performed on both men and women, treating various regions.

Contraindications for Lipolysis:

  • Pregnancy and breastfeeding
  • Infectious conditions
  • Skin diseases in the treated area
  • Acute and medicated phases of malignancies

Side Effects of Lipolysis:

Side effects are very rare. Some may experience localized pain similar to muscle inflammation at the injection site, redness, and swelling, which are short-lived and subside within a few days. Subcutaneous nodules, which resolve with gentle massage, are also occasionally reported as side effects.

Most Commonly Treated Areas:

Double Chin

Usually, 4-5 procedures are sufficient. The result is a younger-looking face with increased skin elasticity, defined contours, and correction of the double chin.

Upper Arms

Lipolysis is also commonly used to correct the arms, shoulders, and forearms.


Lipolytics work to tighten the silhouette, narrow the waist, and correct "muffin top" or fat deposits around the hips.


Lipolysis allows you to slim down the thighs, both on the outer and inner sides, and eliminate cellulite from them.

Knee Area

Lipolysis can remove local imperfections such as excess folds above the knee and overly bulky calves.

After completing a series of treatments, results are seen as a reduction in volume, ranging from 3 to 12 cm, depending on the region.

What to Do After Lipolysis?

After lipolysis, you can resume your usual activities with increased rest for a few days following the procedure. Avoid consuming alcoholic beverages and caffeinated drinks for 24 hours, and refrain from using tanning beds, saunas, steam baths, and engaging in physical activities for 48 to 72 hours after the procedure. It is advisable to increase fluid intake, adjust your diet, and undergo lymphatic drainage after 72 hours.